Researchers from Institut Curie have just published works in Nature that show for the first time that an epigenetic mechanism, based on the "architecture" of genetic material, contributes to the specialization of certain cells of the immune system, called helper T-lymphocytes
A study co-headed by two physician-researchers, Marc-Henri Stern and Olivier Lantz has shown for the first time the possibility to detect circulating tumor DNA in the blood of patients with metastastic eye melanoma.
Dbait molecules, produced in the framework of the research carried out by Marie Dutreix's team at Institut Curie, are currently the object of a phase 1 clinical trial in patients with skin melanoma
A joint Institut Curie/Inserm team headed by Dr. Olivier Delattre has discovered the existence of a new form of bone sarcoma, affecting mainly adolescents and young adults
In a “Perspective” published in Science Translational Medicine, Prof. Daniel LOUVARD, Director of Institut Curie's Research Center, and his colleagues comment the publication of the works of Hans Clevers (Netherlands) and Mamoru Watanabe (Japan) on intestinal tissue regeneration from adult stem cells
Discovered in 1882 by Walther Flemming, chromosomes, the molecular basis of genetic heredity, are still enigmatic, 130 years later. Part of the enigma is starting to be solved, as the team of Edith Heard has just revealed a new layer of their complex organization
Paris, June 22st2011. INCa’s international committee of experts approved Institut Curie’s application, which it deemed“of excellent quality and sufficiently complete”for the SIRIC label to be awarded in 2011.
Prof Michelle Debatisse's team, at Institut Curie, has recently published works in Nature that explain why DNA breaks tend to occur preferentially in specific chromosomal regions, called common fragile sites
Inaugurated on 13 October 2008 by Valérie Pécresse, the Minister of Higher Education and Research, the Center for Developmental Biology and Cancer marks a new stage in the ambitious scientific and medical policy of the Institut Curie.
Following the appeals procedures of 12 to 19 November 2008, the European Patent Office (Munich) has partly gone back on its previous decision, by granting the University of Utah, now owner of the patents of Myriad Genetics, a patent for a certain type of mutation. The University of Utah now in theory “owns” more than half of the identified mutations in the BRCA1 gene.
At the Institut Curie, the Inserm Avenir team “Stress and Cancer”, directed by Fatima Mechta-Grigoriou, has discovered a new mode of action of free radicals in aging
At the Institut Curie, Inserm researchers, in collaboration with collegues from Dynavax1, have discovered a new mechanism controlling the choice in humans between two lines of defence in the event of attack.
Triggering of the cytotoxic immune response requires a long “embrace” between our T cells, which “fight” off intruders (bacteria, viruses, etc), and dendritic cells, which orchestrate the immune response