Séminaire Immunology series
4 avril
2022

Decoding the mode of action of tumor immunotherapies using intravital imaging

Le 4 avril - 11h-23h
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
12 rue Lhomond, Paris 5ème
Description

Understanding complex interactions between the immune system and the tumor microenvironment is an essential step towards the rational development and optimization of immunotherapies. Several experimental approaches are available to tackle this complexity but most are not designed to address the dynamic features of immune reactions, including cell migration, cellular interactions, and transient signaling events. By providing a unique means to access these precious parameters, intravital imaging offers a fresh look at intratumoral immune responses at the single-cell level. We will illustrate how in vivo imaging sheds light on fundamental aspects of tumor immunity and helps elucidate modes of action of immunotherapies such as CAR T cell therapy.

Orateurs
Philippe
Bousso
Dynamics of Immune Responses, Institut Pasteur and Inserm
Invité(es) par
Ana-Maria
Lennon
Olivier
Lantz
Institut Curie
Contact
Elodie
Mieville