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Centre de Recherche
The Curie Institute Research Center
The Institut Curie is a major player in the field of cancer research. It comprises a Hospital and a Research Center with over 1000 employees covering a wide range of nationalities.
The Curie Institute Research Center aims to develop opened-ended science to progress in knowledge while exploiting arising possibilities to improve cancer care by stimulating synergies between research, training and innovation to support patients and serve our society.


Institut Curie (https://institut-curie.org) consists of a cancer hospital and a world-class multidisciplinary Research Centre combining research in cell biology, genetics, epigenetics, immunology, soft matter physics, organic and medicinal chemistry. It includes over 3,300 researchers, physicians, clinicians, technicians and administrative staff working on three sites: Paris, Orsay and Saint-Cloud. The Institute’s facilities include advanced imaging platform with a wide variety of top-of-the-line microscopes from confocal imaging to super-resolution, for live cell and small animal imaging. Other facilities include single cell technologies, small molecule and CRISPR screening, high throughput sequencing, bioinformatics, proteomics and mass spectrometry, antibody technologies and protein purification, nanoSIMS, cytometry, and animal housing (https://institut-curie.org/network/curiecoretech). The proximity of the hospital allows the access to large clinical databases and sample collections as well as an outstanding environment for cancer research.



Institut Curie is recruiting a Junior Group Leader to develop chemical biology approaches to study nucleic acid-related processes (gene regulation, genome integrity) and/or applied to the development of novel diagnostic or therapeutic tools in its Orsay site (south of Paris), close to the Paris-Saclay University research hub. The recruited group leader will benefit from the expertise of the “Chemistry and Modelling for the Biology of Cancer” (CNRS UMR9187 / Inserm U1196) research unit in the design of chemical probes targeting nucleic acid structures and nucleic acid/protein interactions as well as in drug discovery approaches. The applicant is expected to lead projects at the interface between chemistry and biology and his/her activities are expected to cross-fertilize with ongoing research carried out by the biologists located at the Orsay site. This will benefit the creation of an interdisciplinary project (2026) bringing together biologists and chemists mainly working on nucleic acids.

The key criteria for the selection of candidates will be the documented quality of their scientific record, a cutting-edge innovative research project, as well as their capacity to interact with other teams at the Research Centre and Clinical Department of the Institute and beyond, and to drive developments in the field of biomedical research and treatment of cancer as the main mission of Institut Curie.

The newly recruited group will benefit from the access to the local state-of-the-art research equipment and Institut Curie’s core facilities (https://institut-curie.org/network/curiecoretech). Appropriate laboratory space for 6–7 people and a start-up package including salary support will be available. The successful candidate should be committed to apply for third-party funding form national and international agencies, as well as for a permanent position at a French institution (CNRS, INSERM, or Paris Saclay University).



Candidate Profile

Training and Skills required

  • Training: Ph.D. degree in Chemistry, Chemical Biology or any related discipline
  • Professional experience desirable: a successful postdoc experience with excellent publication track record
  • Language skills: English


  • Ability to work independently, managerial abilities, aptitude for working in a team
  • Ability to communicate.


All our opportunities are open to people with disabilities.



Contract information

  • Type of contract: Fixed-term contract.
  • Starting date:  2024
  • Duration: up to 2 years in the meantime of application for a permanent position to Inserm or University
  • Working time: full time
  • Remuneration: according to the current grids
  • Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance
  • Location of the position: Orsay
  • Reference: 2023-11-UMR9187-JPI01




Application should include a cover letter, CV, a list of publications, a brief description of past achievements and research plan (4 pages max.) and names and contact of three referees.


Candidates are encouraged to contact the head of the Chemistry and Modelling for the Biology of cancer research unit,


Publication date: 23rd October 2023

Deadline for application: 31st January 2024. Interviews to be scheduled in April-May 2024



Institut Curie is an inclusive, equal opportunity employer

and is dedicated to the highest standards of research integrity.

Exemple : +33112365489
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