default_medecin

SIMONA CATOZZI

Docteur
Recherche - Saint-Cloud
Spécialités / domaines
Bioinformatique,
Biologie des systèmes,
Cancer,
Centre de Recherche,
Modélisation,
Recherche translationnelle
Présentation

Simona Catozzi obtained her PhD in 2016 in applied mathematics at Institut Non Linéaire de Nice (France) where she contributed to the study of the working principles of intracellular signaling cascades. After two years of sabbatical, she joined the Kiel lab at Systems Biology Ireland in Dublin, where she developed bioinformatic research about Ras-mediated proteomic networks in both physiological and pathological contexts. In 2020, she secured a grant funded by ARC and joined the Institut Curie (France) where she currently works in the Ballesta lab.

Her research focuses on the optimization of personalized chrono-modulated combination therapy for pancreatic cancer patients. The aim of this investigation is to elucidate optimal dose and time of administration by sex, relying on  the analysis of efficacy and toxicity of the standard-of-care treatment (FOLFIRINOX regimen) in association with selected targeted molecules to increase patients' survival.