PerMedCoE: Exascale-ready cell-level simulations for European Personalised Medicine
Personalised medicine opens unexplored frontiers to treating diseases at the individual level combining clinical and omics information. However, the performance of the current simulation software is still insufficient to tackle medical problems such as tumour evolution and response to treatment at the single-cell level or patient-specific treatments. For this reason, this European centre of excellence pursues the following main objectives:
- To optimise key software for cell-level simulations to the new pre-exascale platforms to contribute to the European Personalised Medicine Roadmap.
- To integrate personalised medicine into the new European HPC/Exascale ecosystem, by offering access to HPC/Exascale-adapted and optimised software.
- To design and complete a comprehensive set of personalised medicine use cases to drive the development of cell-level simulations.
- To build the basis for its sustainability by coordinating personalised medicine and HPC communities and reaching out to industrial and academic end-users with use cases, training, expertise and best practices.
The centre will become the entry point to Exascale-ready cell-level simulation software, able to transform personal omics data into actionable mechanistic models of medical relevance, supporting developers and end-users with know-how and best practices. It will also connect simulation software developers with HPC, HTC and HPDA experts at the CoEs POP and HiDALGO, and work with other biomedical consortia such as ELIXIR and LifeTime, also connecting pre- exascale infrastructures hosted by supercomputing centres such as the BSC and CSC.
Further information: www.permedcoe.eu