PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays

Organic & Biomolecular Chemistry
Claire Beauvineau, Corinne Guetta, Marie-Paule Teulade-Fichou, Florence Mahuteau-Betzer
DOI
10.1039/c7ob01705g
Abstract

PhenDV is a light-up probe for G4-fluorescent intercalator displacement. This potent G4-DNA binder discriminates between medium and high-affinity ligands.

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