Identification of new metabolic assets witin the human genome: unveiling new potential targets and reagents against cancer

West EE ... Sitbon M ... Kemper C. Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection.

Immunity. 2023.

Mochel F ... Sitbon M ... De Vivo DC; MetaGlut1 Study Group. Prospective Multicenter Validation of a Simple Blood Test for the Diagnosis of Glut1 Deficiency Syndrome.

Neurology. 2023

Gonzalez-Menendez P ... Sitbon M ... Taylor N. Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A.

Blood. 2023

López-Sánchez U ... Sitbon M*, Battini JL*. Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis.

J Biol Chem. 2020

López-Sánchez U ... Sitbon M. Characterization of XPR1/SLC53A1 variants located outside of the SPX domain in patients with primary familial brain calcification.

Sci Rep. 2019.

Clerc I ... Sitbon M ... Taylor N. Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells.

Nat Metab. 2019

 

Anheim M ... Sitbon M*, Nicolas G*. XPR1 mutations are a rare cause of primary familial brain calcification.

J Neurol. 2016.

Jeziorski E .. Sitbon M*, Courgnaud V*. Searching for Common Mammalian Retroviruses in Pediatric Idiopathic Diseases.

Viruses. 2016.

Laval J ... Sitbon M*, Tirouvanziam R*. Metabolic adaptation of neutrophils in cystic fibrosis airways involves distinct shifts in nutrient transporter expression.

J Immunol. 2013.

Giovannini D ... Sitbon M*, Battini JL*. Inorganic phosphate export by the retrovirus receptor XPR1 in metazoans. Cell Rep. 2013