- Accueil >
- Les séminaires de l’Institut Curie >
- scPRINT: pretraining a foundation model on 50 million cells allows robust zero shot abilities and network inference
scPRINT: pretraining a foundation model on 50 million cells allows robust zero shot abilities and network inference
7 mars - 15h00 - 23h59
Centre de recherche - Paris
Amphithéâtre Hélène Martel-Massignac (BDD)
11 rue Pierre et Marie Curie - 75005 Paris
Description
We present scPRINT, a large transformer model trained on 50 million scRNAseq profiles able to generate cell and gene embeddings, cell labels, denoised expression and cell specific gene networks. We show that novel architectures and training modalities can improve foundation model’s zero shot abilities. We also demonstrate that these models learn gene networks that contain known biological truth.
Orateurs
Jeremie Kalfon
Institut Pasteur / ENS
Invité(es) par
Initiative Single Cell
Institut Curie