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Arc/Arg3.1 governs inflammatory dendritic cell migration from the skin and thereby controls T cell activation

Arc/Arg3.1 governs inflammatory dendritic cell migration from the skin and thereby controls T cell activation

16 sept. 2016Science Immunology

Auteurs

Friederike Ufer, Pablo Vargas, Jan Broder Engler, Joseph Tintelnot, Benjamin Schattling, Hana Winkler, Simone Bauer, Nina Kursawe, Anne Willing, Oliver Keminer, Ora Ohana, Gabriela Salinas-Riester, Ole Pless, Dietmar Kuhl, Manuel A. Friese

Résumé

Arc/Arg3.1 accelerates DC migration by coordinating cytoskeletal changes in response to inflammatory challenges.