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- Computing Individual Risks Based on Family History in Genetic Disease in the Presence of Competing Risks
Computing Individual Risks Based on Family History in Genetic Disease in the Presence of Competing Risks
Auteurs
Gregory Nuel, Alexandra Lefebvre, Olivier Bouaziz
Résumé
When considering a genetic disease with variable age at onset (e.g., familial amyloid neuropathy, cancers), computing the individual risk of the disease based on family history (FH) is of critical interest for both clinicians and patients. Such a risk is very challenging to compute because