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- High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells
High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells
Auteurs
Patricia M. Davidson, Gregory R. Fedorchak, Solenne Mondésert-Deveraux, Emily S. Bell, Philipp Isermann, Denis Aubry, Rachele Allena, Jan Lammerding
Résumé
We report the development, validation, and application of an easy-to-use microfluidic micropipette aspiration device and automated image analysis platform that enables high-throughput measurements of the viscoelastic properties of cell nuclei.