"If you please… draw me a cell". Insights from immune cells

1 mars 2020Journal of Cell Science

DOI : 10.1242/jcs.244806

Auteurs

Hélène D. Moreau, Ana-Maria Lennon-Duménil, Paolo Pierobon

Résumé

ABSTRACT

Studies in recent years have shed light on the particular features of cytoskeleton dynamics in immune cells, challenging the classical picture drawn from typical adherent cell lines. New mechanisms linking the dynamics of the membrane–cytoskeleton interface to the mechanical properties of immune cells have been uncovered and shown to be essential for immune surveillance functions. In this Essay, we discuss these features, and propose immune cells as a new playground for cell biologists who try to understand how cells adapt to different microenvironments to fulfil their functions efficiently.

Membres

ANA-MARIA LENNON DUMENIL

Directeur de recherche Inserm

HELENE MOREAU

Chargé de recherche Inserm