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- MicroRNA-21 Deficiency Alters the Survival of Ly-6C <sup>lo</sup> Monocytes in <i>ApoE</i> <sup>−/−</sup> Mice and Reduces Early-Stage Atherosclerosis—Brief Report
MicroRNA-21 Deficiency Alters the Survival of Ly-6C <sup>lo</sup> Monocytes in <i>ApoE</i> <sup>−/−</sup> Mice and Reduces Early-Stage Atherosclerosis—Brief Report
Auteurs
Anna Chipont, Bruno Esposito, Inès Challier, Mélanie Montabord, Alain Tedgui, Ziad Mallat, Xavier Loyer, Stephane Potteaux
Résumé
Objective—
To determine the role of microRNA-21 (miR-21) on the homeostasis of monocyte subsets and on atherosclerosis development in
Approach and Results—
In
Conclusions—
Gene deletion of miR-21 in