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Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication

29 mai 2020Science Advances

DOI : 10.1126/sciadv.aaz4126

Auteurs

L. Boeckemeier, R. Kraehenbuehl, A. Keszthelyi, M. U. Gasasira, E. G. Vernon, R. Beardmore, C. B. Vågbø, D. Chaplin, S. Gollins, H. E. Krokan, S. A. E. Lambert, B. Paizs, E. Hartsuiker

Résumé

Mre11 exonuclease activity removes gemcitabine from the nascent strand during DNA replication.

Membres

SARAH LAMBERT

Directeur de recherche CNRS