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- PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays
PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays
Auteurs
Claire Beauvineau, Corinne Guetta, Marie-Paule Teulade-Fichou, Florence Mahuteau-Betzer
Résumé
PhenDV is a light-up probe for G4-fluorescent intercalator displacement. This potent G4-DNA binder discriminates between medium and high-affinity ligands.
Membres
CORINNE GUETTA
Ingénieur d'études
FLORENCE MAHUTEAU-BETZER
Directeur de recherche CNRS
