Xenopus Protein Atlas: missing proteins turn up in frogs !

6 novembre - 11h00 - 23h59

Centre de recherche - Orsay

Amphithéâtre du Bâtiment 111

Campus universitaire, Orsay (91)

Description

Understanding protein expression across tissues and organisms is crucial for elucidating functional similarities and differences in physiological processes, which is essential for selecting the appropriate model organism in biomedical studies. We present a comprehensive analysis of protein repertoires across 25 tissues in Xenopus frogs, using advanced quantitative mass spectrometry to measure the levels of over 15,000 proteins. By comparing these profiles, we reveal tissue-specific expression patterns and identify conserved proteins shared across diverse organs. We explore evolutionary strategies of ubiquitous and tissue-specific proteins and discuss the search for 'missing' proteins that have vanished in human samples but appear in frogs.

Orateurs

Leon Peshkin

Harvard Medical School

Invité(es) par

Anne-Hélène MONSORO-BURQ

Institut Curie

Une question sur le séminaire ?

Anne-Hélène MONSORO-BURQ

anne-helene.monsoro-burq@curie.fr