ANDRE BORTOLINI SILVEIRA

Docteur

Recherche - Paris

Spécialités / domaines

Bioinformatique,

Biologie moléculaire,

Cancer,

Cytométrie en flux,

Hétérogénéité,

Single Cell

Fonctions au sein de l'Institut Curie :

Chercheur post-doctorant

Réparation de l'ADN et Mélanome Uvéal (D.R.U.M)
Unité : Cancer, Hétérogénéité, Instabilité et Plasticité - CHIP (U830)

Présentation

Andre BORTOLINI SILVEIRA is a Post-Doctoral Researcher in DRUM team (Stern Lab) of Institut Curie's Research Center. He is currently in charge of the current research projects:

- Transcriptomic and epigenomic analysis os Uveal Melanoma and it's cell-of-origin, choroidal melanocytes

- Epigenetic landscape of MBD4-deficient Uveal Melanomas

- Centromeric instability in Uveal Melanoma

Publications

2021

Multimodal liquid biopsy for early monitoring and outcome prediction of chemotherapy in metastatic breast cancer

npj Breast Cancer

Amanda Bortolini Silveira, François-Clément Bidard, Marie-Laure Tanguy, Elodie Girard, Olivier Trédan, Coraline Dubot, William Jacot, Anthony Goncalves, Marc Debled, Christelle Levy, Jean-Marc Ferrero, Christelle Jouannaud, Maria Rios, Marie-Ange Mouret-Reynier, Florence Dalenc, Caroline Hego, Aurore Rampanou, Benoit Albaud, Sylvain Baulande, Frédérique Berger, Jérôme Lemonnier, Shufang Renault, Isabelle Desmoulins, Charlotte Proudhon, Jean-Yves Pierga

(2021 déc 01)

2019

Transposition favors the generation of large effect mutations that may facilitate rapid adaption

Nature Communications

Leandro Quadrana, Mathilde Etcheverry, Arthur Gilly, Erwann Caillieux, Mohammed-Amin Madoui, Julie Guy, Amanda Bortolini Silveira, Stefan Engelen, Victoire Baillet, Patrick Wincker, Jean-Marc Aury, Vincent Colot

(2019 déc 01)

2018

Single Droplet Digital Polymerase Chain Reaction for Comprehensive and Simultaneous Detection of Mutations in Hotspot Regions

Journal of Visualized Experiments

Charles Decraene, Amanda Bortolini Silveira, Marc Michel, François-Clément Bidard, Jean-Yves Pierga, Marc-Henri Stern, Charlotte Proudhon

(2018 Sep 25)

2015

Lymphotoxin-β receptor in microenvironmental cells promotes the development of T-cell acute lymphoblastic leukaemia with cortical/mature immunophenotype

British Journal of Haematology

Mónica T. Fernandes, Marinella N. Ghezzo, André B. Silveira, Ravi K. Kalathur, Vanda Póvoa, Ana R. Ribeiro, Sílvia R. Brandalise, Emmanuel Dejardin, Nuno L. Alves, Jacques Ghysdael, João T. Barata, José Andres Yunes, Nuno R. dos Santos

(2015 déc 01)

2015

N-(1′-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia

European Journal of Medicinal Chemistry

Lívia B. Salum, Alessandra Mascarello, Rafael R. Canevarolo, Wanessa F. Altei, Angelo B.A. Laranjeira, Patrícia D. Neuenfeldt, Taisa R. Stumpf, Louise D. Chiaradia-Delatorre, Laura L. Vollmer, Hikmat N. Daghestani, Carolina P. de Souza Melo, André B. Silveira, Paulo C. Leal, Marisa J.S. Frederico, Leandro F. do Nascimento, Adair R.S. Santos, Adriano D. Andricopulo, Billy W. Day, Rosendo A. Yunes, Andreas Vogt, José A. Yunes, Ricardo J. Nunes

(2015 mai 01)