GERALDINE BUHAGIAR

Recherche - Orsay

Spécialités / domaines

Biologie cellulaire,

Biologie moléculaire,

Recherche fondamentale

Fonctions au sein de l'Institut Curie :

Ingénieur d'études
Instabilité génétique et cancérogénèse
Unité : Intégrité du génome, ARN et Cancer (UMR3348)

Publications

2020

A decrease in NAMPT activity impairs basal PARP-1 activity in cytidine deaminase deficient-cells, independently of NAD+

Scientific Reports

Sandra Cunha Silveira, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Simon Gemble, Elias Bou Samra, Hamza Mameri, Patricia Duchambon, Christelle Machon, Jérôme Guitton, Mounira Amor-Guéret

(2020 déc 01)

2020

Topoisomerase IIα prevents ultrafine anaphase bridges by two mechanisms

Open Biology

Simon Gemble, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Gaëlle Fontaine, Sarah Lambert, Mounira Amor-Guéret

(2020 mai 01)

2017

A role for Tau protein in maintaining ribosomal DNA stability and cytidine deaminase-deficient cell survival

Nature Communications

Elias Bou Samra, Géraldine Buhagiar-Labarchède, Christelle Machon, Jérôme Guitton, Rosine Onclercq-Delic, Michael R. Green, Olivier Alibert, Claude Gazin, Xavier Veaute, Mounira Amor-Guéret

(2017 déc 01)

2016

A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation

Journal of Cell Science

Simon Gemble, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Denis Biard, Sarah Lambert, Mounira Amor-Guéret

(2016 jan 01)

2015

Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA

PLOS Genetics

Simon Gemble, Akshay Ahuja, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Julien Dairou, Denis S. F. Biard, Sarah Lambert, Massimo Lopes, Mounira Amor-Guéret

(2015 Juil 16)

2012

Bloom’s Syndrome and PICH Helicases Cooperate with Topoisomerase IIα in Centromere Disjunction before Anaphase

PLOS ONE

Sébastien Rouzeau, Fabrice P. Cordelières, Géraldine Buhagiar-Labarchède, Ilse Hurbain, Rosine Onclercq-Delic, Simon Gemble, Laura Magnaghi-Jaulin, Christian Jaulin, Mounira Amor-Guéret

(2012 avr 26)

2011

Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome

Nature Communications

Pauline Chabosseau, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Sarah Lambert, Michelle Debatisse, Olivier Brison, Mounira Amor-Guéret

(2011 Sep 01)

2010

The Bloom Syndrome Protein Limits the Lethality Associated with RAD51 Deficiency

Molecular Cancer Research

Kenza Lahkim Bennani-Belhaj, Sébastien Rouzeau, Géraldine Buhagiar-Labarchède, Pauline Chabosseau, Rosine Onclercq-Delic, Emilie Bayart, Fabrice Cordelières, Jérôme Couturier, Mounira Amor-Guéret

(2010 Mar 01)

2010

BLM Deficiency Is Not Associated with Sensitivity to Hydroxyurea-Induced Replication Stress

Journal of Nucleic Acids

Kenza Lahkim Bennani-Belhaj, Géraldine Buhagiar-Labarchède, Nada Jmari, Rosine Onclercq-Delic, Mounira Amor-Guéret

(2010 jan 01)