NATHALIE BERTHAULT

CNRS

Recherche - Orsay

Spécialités / domaines

Bioinformatique,

Biologie cellulaire,

Imagerie Cellulaire et Tissulaire,

Radiobiologie

Fonctions au sein de l'Institut Curie :

Assistant ingénieur

Réparation, Radiation et Thérapies innovantes anticancer
Unité : Signalisation, radiobiologie et cancer (UMR3347 / U1021)

Publications

2024

Differential Remodeling of the Oxylipin Pool After FLASH Versus Conventional Dose-Rate Irradiation In Vitro and In Vivo

International Journal of Radiation Oncology*Biology*Physics

Lucie Portier, Patricia Daira, Baptiste Fourmaux, Sophie Heinrich, Margaux Becerra, Charles Fouillade, Nathalie Berthault, Marie Dutreix, Arturo Londoño-Vallejo, Pierre Verrelle, Nathalie Bernoud-Hubac, Vincent Favaudon

(2024 fév 01)

2024

The AsiDNA™ decoy mimicking DSBs protects the normal tissue from radiation toxicity through a DNA-PK/p53/p21-dependent G1/S arrest

NAR Cancer

Anouk Sesink, Margaux Becerra, Jia-Ling Ruan, Sophie Leboucher, Maxime Dubail, Sophie Heinrich, Wael Jdey, Kristoffer Petersson, Charles Fouillade, Nathalie Berthault, Marie Dutreix, Pierre-Marie Girard

(2024 jan 09)

2023

Lung Organotypic Slices Enable Rapid Quantification of Acute Radiotherapy Induced Toxicity

Cells

Maxime Dubail, Sophie Heinrich, Lucie Portier, Jessica Bastian, Lucia Giuliano, Lilia Aggar, Nathalie Berthault, José-Arturo Londoño-Vallejo, Marta Vilalta, Gael Boivin, Ricky A. Sharma, Marie Dutreix, Charles Fouillade

(2023 oct 11)

2022

Inhibition of DNA Repair by Inappropriate Activation of ATM, PARP, and DNA-PK with the Drug Agonist AsiDNA

Cells

Nathalie Berthault, Ptissam Bergam, Floriane Pereira, Pierre-Marie Girard, Marie Dutreix

(2022 Juil 08)

2020

Evolution of tumor cells during AsiDNA treatment results in energy exhaustion, decrease in responsiveness to signal, and higher sensitivity to the drug

Evolutionary Applications

Pierre‐Marie Girard, Nathalie Berthault, Maria Kozlac, Sofia Ferreira, Wael Jdey, Srividya Bhaskara, Sergey Alekseev, Frederic Thomas, Marie Dutreix

(2020 Aoû 01)

2019

Preclinical Studies Comparing Efficacy and Toxicity of DNA Repair Inhibitors, Olaparib, and AsiDNA, in the Treatment of Carboplatin-Resistant Tumors

Frontiers in Oncology

Nirmitha I. Herath, Nathalie Berthault, Sylvain Thierry, Wael Jdey, Marie-Christine Lienafa, Françoise Bono, Patricia Noguiez-Hellin, Jian-Sheng Sun, Marie Dutreix

(2019 nov 12)

2019

Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models

Frontiers in Oncology

Julian Biau, Emmanuel Chautard, Nathalie Berthault, Leanne de Koning, Frank Court, Bruno Pereira, Pierre Verrelle, Marie Dutreix

(2019 juin 19)

2015

DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasion

Cell Cycle

Ewa Kotula, Nathalie Berthault, Celine Agrario, Marie-Christine Lienafa, Anthony Simon, Florent Dingli, Damarys Loew, Vonick Sibut, Simon Saule, Marie Dutreix

(2015 juin 18)