Diacylglycerol kinase ζ promotes actin cytoskeleton remodeling and mechanical forces at the B cell immune synapse

Science Signaling
Sara V. Merino-Cortés, Sofia R. Gardeta, Sara Roman-Garcia, Ana Martínez-Riaño, Judith Pineau, Rosa Liebana, Isabel Merida, Ana-Maria Lennon Dumenil, Paolo Pierobon, Julien Husson, Balbino Alarcon, Yolanda R. Carrasco
DOI
10.1126/scisignal.aaw8214
Abstract

Optimal B cell responses depend on balanced signaling between DAG and phosphatidic acid, which is regulated by diacylglycerol kinase ζ.

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