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LKB1 specifies neural crest cell fates through pyruvate-alanine cycling

5 juil. 2019Science Advances

DOI : 10.1126/sciadv.aau5106

Auteurs

Anca G. Radu, Sakina Torch, Florence Fauvelle, Karin Pernet-Gallay, Anthony Lucas, Renaud Blervaque, Véronique Delmas, Uwe Schlattner, Laurence Lafanechère, Pierre Hainaut, Nicolas Tricaud, Véronique Pingault, Nadège Bondurand, Nabeel Bardeesy, Lionel Larue, Chantal Thibert, Marc Billaud

Résumé

Glial specification of neural crest cells requires the tumor suppressor LKB1-mediated action on alanine biosynthesis.

Membres

LIONEL LARUE

Directeur de recherche Inserm