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Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice

16 juil. 2014Science Translational Medicine

DOI : 10.1126/scitranslmed.3008973

Auteurs

Vincent Favaudon, Laura Caplier, Virginie Monceau, Frédéric Pouzoulet, Mano Sayarath, Charles Fouillade, Marie-France Poupon, Isabel Brito, Philippe Hupé, Jean Bourhis, Janet Hall, Jean-Jacques Fontaine, Marie-Catherine Vozenin

Résumé

Pulsed, ultrahigh dose-rate irradiation is safer than standard radiotherapy for the treatment of lung cancer and selectively spares normal tissue.