- Accueil >
- Les séminaires de l’Institut Curie >
- RNA-binding proteins in cancer: lessons from CSDE1
RNA-binding proteins in cancer: lessons from CSDE1
Centre de recherche - Orsay
Amphithéâtre du Bâtiment 111
Campus universitaire, Orsay (91)
Description
"RNA-binding proteins (RBPs) modulate all aspects of post-transcriptional gene expression and are increasingly recognized as essential for cancer cell adaptation, reprogramming and stress survival. We aim to identify novel vulnerabilities of metastatic cells that could be harnessed for cancer treatment. My talk will focus on the RNA-binding protein UNR/CSDE1, a protein conserved from flies to humans for which we found a role in melanoma metastasis. I will explain our efforts to untangle the molecular mechanisms of CSDE1 function, its context-specific roles in cancer, and the identification of features that could be targeted for regulation”.
Orateurs
Fatima GEBAUER HERNANDEZ
Centre for Genomic Regulation (CRG)
Invité(es) par
Stéphan VAGNER
Institut Curie