ANTON GRANZHAN

Docteur,

Chargé de recherche CNRS

Recherche - Orsay

Spécialités / domaines

Biologie et chimie des radiations, signalisation cellulaire et cancer,

Chimie

Fonctions au sein de l'Institut Curie :

Chef d'équipe de recherche

Chimie et Reconnaissance d'acides nucléiques
Unité : Chimie et Modélisation pour la Biologie du Cancer (UMR9187 / U1196)

Publications

2023

Solution and Gas-Phase Stability of DNA Junctions from Temperature-Controlled Electrospray Ionization and Surface-Induced Dissociation

Analytical Chemistry

Adam Pruška, Julian A. Harrison, Anton Granzhan, Adrien Marchand, Renato Zenobi

(2023 Sep 12)

2023

Optimization of G‐Quadruplex Ligands through a SAR Study by Combining Parallel Synthesis and Screening of Cationic Bis(acylhydrazones)

Chemistry – A European Journal

Oksana Reznichenko, Denis Leclercq, Jaime Franco Pinto, Liliane Mouawad, Valérie Gabelica, Anton Granzhan

(2023 jan 18)

2023

Novel Synthesis of IMC-48 and Affinity Evaluation with Different i-Motif DNA Sequences

Molecules

Florian Berthiol, Joseph Boissieras, Hugues Bonnet, Marie Pierrot, Christian Philouze, Jean-François Poisson, Anton Granzhan, Jérôme Dejeu, Eric Defrancq

(2023 jan 10)

2022

The different activities of RNA G-quadruplex structures are controlled by flanking sequences

Life Science Alliance

Alice J-L Zheng, Aikaterini Thermou, Pedro Guixens Gallardo, Laurence Malbert-Colas, Chrysoula Daskalogianni, Nathan Vaudiau, Petter Brohagen, Anton Granzhan, Marc Blondel, Marie-Paule Teulade-Fichou, Rodrigo Prado Martins, Robin Fahraeus

(2022 fév 01)

2022

Acridine–O6-benzylguanine hybrids: Synthesis, DNA binding, MGMT inhibition and antiproliferative activity

European Journal of Medicinal Chemistry

Jaime Franco Pinto, Alexandra Fillion, Patricia Duchambon, Sophie Bombard, Anton Granzhan

(2022 jan 01)

2022

Assessment of presumed small-molecule ligands of telomeric i-DNA by BioLayer Interferometry (BLI)

Chemical Communications

Hugues Bonnet, Maeva Morel, Alexandre Devaux, Joseph Boissieras, Anton Granzhan, Benjamin Elias, Thomas Lavergne, Jérôme Dejeu, Eric Defrancq

(2022 jan 01)

2022

Harnessing an emissive guanine surrogate to design small-molecule fluorescent chemosensors of <i>O</i><sup>6</sup>-methylguanine-DNA-methyltransferase (MGMT)

Organic & Biomolecular Chemistry

Alexandra Fillion, Jaime Franco Pinto, Anton Granzhan

(2022 jan 01)

2021

Dual targeting of higher-order DNA structures by azacryptands induces DNA junction-mediated DNA damage in cancer cells

Nucleic Acids Research

Joanna Zell, Katerina Duskova, Leïla Chouh, Madeleine Bossaert, Nicolas Chéron, Anton Granzhan, Sébastien Britton, David Monchaud

(2021 oct 11)

2021

Identifying G-Quadruplex-DNA-Disrupting Small Molecules

Journal of the American Chemical Society

Jérémie Mitteaux, Pauline Lejault, Filip Wojciechowski, Alexandra Joubert, Julien Boudon, Nicolas Desbois, Claude P. Gros, Robert H. E. Hudson, Jean-Baptiste Boulé, Anton Granzhan, David Monchaud

(2021 Aoû 18)

2021

SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction

Nucleic Acids Research

Marc Lavigne, Olivier Helynck, Pascal Rigolet, Rofia Boudria-Souilah, Mireille Nowakowski, Bruno Baron, Sébastien Brülé, Sylviane Hoos, Bertrand Raynal, Lionel Guittat, Claire Beauvineau, Stéphane Petres, Anton Granzhan, Jean Guillon, Geneviève Pratviel, Marie-Paule Teulade-Fichou, Patrick England, Jean-Louis Mergny, Hélène Munier-Lehmann

(2021 Juil 21)