PATRICIA DUCHAMBON

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Ingénieur d'études Inserm

Recherche - Orsay

Spécialités / domaines

Protéines recombinantes

Fonctions au sein de l'Institut Curie :

Ingénieur d'études

Médicaments et sondes pour les structures secondaires des acides nucléiques
Unité : Chimie et Modélisation pour la Biologie du Cancer (UMR9187 / U1196)

Publications

2024

Light‐Activatable Photocaged UNC2025 for Triggering TAM Kinase Inhibition in Bladder Cancer

ChemBioChem

Chloé Breton-Patient, Sébastien Billotte, Patricia Duchambon, Gaëlle Fontaine, Sophie Bombard, Sandrine Piguel

(2024 fév 16)

2022

Type I arginine methyltransferases are intervention points to unveil the oncogenic Epstein-Barr virus to the immune system

Nucleic Acids Research

Gaelle Angrand, Alicia Quillévéré, Nadège Loaëc, Van-Trang Dinh, Ronan Le Sénéchal, Rahima Chennoufi, Patricia Duchambon, Marc Keruzoré, Rodrigo Prado Martins, Marie-Paule Teulade-Fichou, Robin Fåhraeus, Marc Blondel

(2022 nov 11)

2022

Protein Dimerization via Tyr Residues: Highlight of a Slow Process with Co-Existence of Numerous Intermediates and Final Products

International Journal of Molecular Sciences

Anouchka Gatin, Patricia Duchambon, Guillaume van der Rest, Isabelle Billault, Cécile Sicard-Roselli

(2022 jan 21)

2022

Acridine–O6-benzylguanine hybrids: Synthesis, DNA binding, MGMT inhibition and antiproliferative activity

European Journal of Medicinal Chemistry

Jaime Franco Pinto, Alexandra Fillion, Patricia Duchambon, Sophie Bombard, Anton Granzhan

(2022 jan 01)

2021

BrdU immuno-tagged G-quadruplex ligands: a new ligand-guided immunofluorescence approach for tracking G-quadruplexes in cells

Nucleic Acids Research

Thibaut Masson, Corinne Landras Guetta, Eugénie Laigre, Anne Cucchiarini, Patricia Duchambon, Marie-Paule Teulade-Fichou, Daniela Verga

(2021 déc 16)

2021

Oxidative radicals (HO• or N3•) induce several di-tyrosine bridge isomers at the protein scale

Free Radical Biology and Medicine

Anouchka Gatin, Isabelle Billault, Patricia Duchambon, Guillaume Van der Rest, Cécile Sicard-Roselli

(2021 jan 01)

2020

A decrease in NAMPT activity impairs basal PARP-1 activity in cytidine deaminase deficient-cells, independently of NAD+

Scientific Reports

Sandra Cunha Silveira, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, Simon Gemble, Elias Bou Samra, Hamza Mameri, Patricia Duchambon, Christelle Machon, Jérôme Guitton, Mounira Amor-Guéret

(2020 déc 01)

2020

Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

Nature Communications

Åsa Ehlén, Charlotte Martin, Simona Miron, Manon Julien, François-Xavier Theillet, Virginie Ropars, Gaetana Sessa, Romane Beaurepere, Virginie Boucherit, Patricia Duchambon, Ahmed El Marjou, Sophie Zinn-Justin, Aura Carreira

(2020 déc 01)

2020

Nucleolin Discriminates Drastically between Long-Loop and Short-Loop Quadruplexes

Biochemistry

Abhijit Saha, Patricia Duchambon, Vanessa Masson, Damarys Loew, Sophie Bombard, Marie-Paule Teulade-Fichou

(2020 Mar 31)

2014

How protein structure affects redox reactivity: example of Human centrin 2

Phys. Chem. Chem. Phys.

Abdeslam Et Taouil, Emilie Brun, Patricia Duchambon, Yves Blouquit, Manon Gilles, Emmanuel Maisonhaute, Cécile Sicard-Roselli

(2014 jan 01)