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Asymmetric axonal edge guidance: a new paradigm for building oriented neuronal networks

1 janv. 2016Lab on a Chip

DOI : 10.1039/c6lc00479b

Auteurs

Renaud Renault, Jean-Baptiste Durand, Jean-Louis Viovy, Catherine Villard

Résumé

We present a novel kind of directional axon guides for brain-on-a-chip applications. The axonal directional selectivity is created by rerouting axons growing in the unwanted direction back to their original compartment while leaving the other growth direction unaffected.