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- Building bridges to move recombination complexes
Building bridges to move recombination complexes
Auteurs
Emeline Dubois, Arnaud De Muyt, Jessica L. Soyer, Karine Budin, Mathieu Legras, Tristan Piolot, Robert Debuchy, Nancy Kleckner, Denise Zickler, Eric Espagne
Résumé
Significance
The central feature of meiosis is pairing and recombination of homologous maternal and paternal chromosomes (homologs). Homolog axes become first coaligned at a certain distance; they then synapse by synaptonemal complex (SC) formation. We show that the structural and molecular pathway by which chromosomes transit from coalignment to the SC state in the fungus