Quantifying nanotherapeutic penetration using a hydrogel-based microsystem as a new 3D in vitro platform

Lab on a Chip
Saba Goodarzi, Audrey Prunet, Fabien Rossetti, Guillaume Bort, Olivier Tillement, Erika Porcel, Sandrine Lacombe, Ting-Di Wu, Jean-Luc Guerquin-Kern, Hélène Delanoë-Ayari, François Lux, Charlotte Rivière
DOI
10.1039/d1lc00192b
Abstract

We present a simple yet highly flexible 3D-model microsystem for the investigation of nanotherapeutics transport, ahead of in vivo studies, allowing to follow the penetration and distribution of nanoparticles within spheroids over space and time.

Équipes / Plateformes
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