Assessment of presumed small-molecule ligands of telomeric i-DNA by BioLayer Interferometry (BLI)

Nom de la revue
Chemical Communications
Hugues Bonnet, Maeva Morel, Alexandre Devaux, Joseph Boissieras, Anton Granzhan, Benjamin Elias, Thomas Lavergne, Jérôme Dejeu, Eric Defrancq

Biolayer interferometry and circular dichroism spectroscopy were used to investigate the interaction between previously reported i-motif DNA ligands and folded or unfolded i-DNA in acidic (pH 5.5) and near-neutral (pH 6.5) conditions.