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- ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
Auteurs
Matthew Raab, Matteo Gentili, Henry de Belly, Hawa-Racine Thiam, Pablo Vargas, Ana Joaquina Jimenez, Franziska Lautenschlaeger, Raphaël Voituriez, Ana-Maria Lennon-Duménil, Nicolas Manel, Matthieu Piel
Résumé
Repairing tears in the nuclear envelope
The nuclear envelope segregates genomic DNA from the cytoplasm and regulates protein trafficking between the cytosol and the nucleus. Maintaining nuclear envelope integrity during interphase is considered crucial. However, Raab
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