ALBERTAS NAVICKAS

Docteur,

Chargé de recherche Inserm

Recherche - Orsay

Spécialités / domaines

ARN,

Biologie moléculaire,

Cancer,

Génomique,

Single Cell

Fonctions au sein de l'Institut Curie :

Chef d'équipe de recherche

ARN, microenvironnement tumoral et métastase
Unité : Intégrité du génome, ARN et Cancer (UMR3348)

Présentation

Albertas Navickas est le responsable de l'équipe "ARN, microenvironnement tumoral et métastase", s'intéressant aux réseaux de régulation génique impliqués dans la progression métastatique. Son laboratoire combine les modèles d'organoïdes dérivés de cellules souches humaines avec les approches génomiques à l'échelle de cellules uniques pour étudier les interactions à distance entre les cellules tumorales et la niche métastatique.

Publications

2023

Integrative identification of non-coding regulatory regions driving metastatic prostate cancer

bioRxiv

2023

A bi-steric mTORC1-selective inhibitor overcomes drug resistance in breast cancer

Oncogene

Delong Meng, Xin Zhao, Yu Chi Yang, Albertas Navickas, Ciara Helland, Hani Goodarzi, Mallika Singh, Sourav Bandyopadhyay

(2023 Juil 07)

2023

An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus

Nature Cell Biology

Albertas Navickas, Hosseinali Asgharian, Juliane Winkler, Lisa Fish, Kristle Garcia, Daniel Markett, Martin Dodel, Bruce Culbertson, Sohit Miglani, Tanvi Joshi, Keyi Yin, Phi Nguyen, Steven Zhang, Nicholas Stevers, Hun-Way Hwang, Faraz Mardakheh, Andrei Goga, Hani Goodarzi

(2023 juin 01)

2023

A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expression

Nature Cancer

Bruce Culbertson, Kristle Garcia, Daniel Markett, Hosseinali Asgharian, Li Chen, Lisa Fish, Albertas Navickas, Johnny Yu, Brian Woo, Arjun Scott Nanda, Benedict Choi, Shaopu Zhou, Joshua Rabinowitz, Hani Goodarzi

(2023 mai 11)

2023

Revealing the Grammar of Small RNA Secretion Using Interpretable Machine Learning

bioRxiv

Bahar Zirak, Mohsen Naghipourfar, Ali Saberi, Delaram Pouyabahar, Amirhossein Zarezadeh, Lixi Luo, Lisa Fish, Doowon Huh, Albertas Navickas, Ali Sharifi-Zarchi, Hani Goodarzi

(2023 avr 20)

2023

A systematic search for RNA structural switches across the human transcriptome

bioRxiv

Matvei Khoroshkin, Daniel Asarnow, Albertas Navickas, Aidan Winters, Johnny Yu, Simon K. Zhou, Shaopu Zhou, Christina Palka, Lisa Fish, K. Mark Ansel, Yifan Cheng, Luke A. Gilbert, Hani Goodarzi

(2023 Mar 12)

2023

Systematic Identification of Post-Transcriptional Regulatory Modules

bioRxiv

Matvei Khoroshkin, Andrey Buyan, Martin Dodel, Albertas Navickas, Johnny Yu, Fathima Trejo, Anthony Doty, Rithvik Baratam, Shaopu Zhou, Tanvi Joshi, Kristle Garcia, Benedict Choi, Sohit Miglani, Vishvak Subramanyam, Hailey Modi, Daniel Markett, M. Ryan Corces, Ivan V. Kulakovskiy, Faraz Mardakheh, Hani Goodarzi

(2023 Mar 01)

2023

Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma

bioRxiv

Ryan M. Samuel, Albertas Navickas, Ashley Maynard, Eliza A. Gaylord, Kristle Garcia, Samyukta Bhat, Homa Majd, Mikayla N. Richter, Nicholas Elder, Daniel Le, Phi Nguyen, Bradley Shibata, Marta Losa Llabata, Licia Selleri, Diana J. Laird, Spyros Darmanis, Hani Goodarzi, Faranak Fattahi

(2023 Mar 01)

2021

Author Correction: Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior

Nature Communications

J. Blaze, A. Navickas, H. L. Phillips, S. Heissel, A. Plaza-Jennings, S. Miglani, H. Asgharian, M. Foo, C. D. Katanski, C. P. Watkins, Z. T. Pennington, B. Javidfar, S. Espeso-Gil, B. Rostandy, H. Alwaseem, C. G. Hahn, H. Molina, D. J. Cai, T. Pan, W. D. Yao, H. Goodarzi, F. Haghighi, S. Akbarian

(2021 déc 01)

2021

Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior

Nature Communications

(2021 déc 01)