CLAIRE WILHELM

Claire Wilhelm, principal investigator of the NanoBioMag team, has oriented her research to the biomedical field since obtaining her PhD in 2003 in soft matter physics. This last decade, she used her knowledge of biophysics and materials science to advance the field of nanomedicine. The goal has been to provide the fullest possible picture of the modes of action and fates of (magnetic) nanoparticles in their biological target environments. In doing so, she has worked mostly (i) in biophysics and (ii) in physical chemistry interfacing with therapy. The former has been awarded an ERC consolidator in 2014 (MaTissE) and an ERC proof of concept in 2021 (BioMag) and led to the development of magnetic-based methods to manipulate living cells, explore tissue mechanics, and provide magnetic artificial tissue replacements. The latter has also been awarded an ERC consolidator in 2019 (NanoBioMade). It was founded on previous works proposing combined cancer solutions by applying multiple stimuli to the same nanoparticle, introducing the use of magnetic nanoparticles as photothermal tools, and developing extracellular vesicles engineering with nanoparticles and drugs as bio-camouflaged vectors. One bridging theme between these two areas of expertise has been whether and how nanoparticles properties can be affected once achieving their therapeutic mission, as they journey within their cellular. 

Claire Wilhelm was appointed CNRS research director (DR2)  in 2013 and senior research director (DR1) in 2018. She received the CNRS bronze medal in 2011, the Louis Ancel prize in 2014, and the CNRS silver medal in 2022. She has co-authored 190+ publications (17 000+ citations, h-index 69), 7 patents, and she delivered 70+ invited lectures.

NanoBioMag Team

NanoBioMag Works 1 : Magnetic Tissue Bioengineering.

NanoBioMag Works 2 : Nano-Therapies.

NanoBioMag Works 3 : Nanoparticles fate and transport in extracellular vesicles.

NanoBioMag Project 1 : Biogenic photo-responsive vectors in nanomedicine.

NanoBioMag Project 2 : Magnetic tissue stretcher.