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Unité
PASCAL HERSEN / MATHIEU COPPEY / ANTOINE COULON
Physique des Cellules et Cancer (UMR168)

Le laboratoire Physico Chimie Curie, pionnier de l’interface entre la physique, la chimie et la biologie, depuis sa création en 1996, est un laboratoire de recherche interdisciplinaire explorant le rôle des lois physiques dans l’architecture et les fonctions des systèmes cellulaires.

Chiffres-clés
150
physiciens, chimistes et biologistes dont 35 chercheurs, 39 doctorants, 31 postdoctorants et 28 techniciens et ingénieurs
13
Equipes de recherche labelisées par les grandes agences de financements (ERC, ANR, H2020, FRM, ARC, La Ligue, etc…)
4
plateaux techniques en biochimie et biologie moléculaire, microfluidique, microfabrication, microscopie électronique
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Événements scientifiques
17 Juil
2024
Séminaire
11h-23h
Centre de recherche - Paris - Amphithéâtre Marie Curie
Bioengineering Human Embryo and Organ Models
Early human development remains mysterious and difficult to study.  Recent advances in developmental biology, stem cell biology and bioengineering have contributed to a significant interest in constructing controllable, stem cell-based models of human embryo and organs (embryoids / organoids).  The controllability and reproducibility of these human development models, coupled with the ea
3 Juil
2024
Séminaire
11h-23h
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
Molecular assembly and mechanics of single vimentin intermediate filaments
Intermediate filaments (IF) are involved in key cellular functions including polarization, migration, and protection against large deformations. These functions are related to their remarkable ability to extend without breaking, a capacity that should be determined by the molecular organization of subunits within filaments. However, this structure-mechanics relationship remains poorly understood a
26 juin
2024
Séminaire
11h-23h
Centre de recherche - Paris - Amphithéâtre Marie Curie
Bees, flowers and electrostatics: a window on a new sensory ecology
Working together to exchange nutrition for pollination services, bees and flowers interact relying on vision, olfaction, touch, and humidity sensing. We have discovered that bees can also detect and learn about the weak electric field that arises as they approach a flower. This electric field – a small force-  is gene
24 juin
2024
Séminaire
14h-23h
Centre de recherche - Paris - Amphithéâtre Marie Curie
Self-assembled active actomyosin gels spontaneously curve and wrinkle similar to biological cells and tissues
Living systems adopt a diversity of curved and highly dynamic shapes. These diverse morphologies appear on many length-scales, from cells to tissues and organismal scales. The common driving force for these dynamic shape changes are contractile stresses generated by myosin motors in the cell cytoskeleton, that converts chemical energy into mechanical work. A good understanding of how contractile s
20 juin
2024
Séminaire
11h-23h
Centre de recherche - Paris - Amphithéâtre Marie Curie
Hydra morphogenesis as phase transition Dynamics
A remarkable hallmark of animal morphogenesis is the robust convergence of this process into a stereotypic body form of a viable organism. Hydra regeneration provides a unique experimental setup, allowing us to develop a physics framework for this pattern-formation process. We demonstrated before that by tuning an external electric field, we can drive morphogenesis in whole-body Hydra regeneration
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