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Unité
PASCAL HERSEN / MATHIEU COPPEY / ANTOINE COULON
Physique des Cellules et Cancer (UMR168)

Le laboratoire Physico Chimie Curie, pionnier de l’interface entre la physique, la chimie et la biologie, depuis sa création en 1996, est un laboratoire de recherche interdisciplinaire explorant le rôle des lois physiques dans l’architecture et les fonctions des systèmes cellulaires.

Chiffres-clés
150
physiciens, chimistes et biologistes dont 35 chercheurs, 39 doctorants, 31 postdoctorants et 28 techniciens et ingénieurs
13
Equipes de recherche labelisées par les grandes agences de financements (ERC, ANR, H2020, FRM, ARC, La Ligue, etc…)
4
plateaux techniques en biochimie et biologie moléculaire, microfluidique, microfabrication, microscopie électronique
Publications clés
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Actualités
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Événements scientifiques
11 Sep
2024
Séminaire
11h-23h
Centre de recherche - Paris - Amphithéâtre Marie Curie
From perception to action without nerves and muscles: lessons from plants
As sessile organisms, plants face a constantly changing environment with no means of escape. Thus, despite their lack of nerves and muscles, they have evolved unique mechanisms to perceive and respond to external physical signals. In this seminar, I will illustrate this ability through two emblematic plant responses. First, I will discuss plant gravitropism - the growth response and reorientation
17 Juil
2024
Séminaire
11h-23h
Centre de recherche - Paris - Amphithéâtre Marie Curie
Bioengineering Human Embryo and Organ Models
Early human development remains mysterious and difficult to study.  Recent advances in developmental biology, stem cell biology and bioengineering have contributed to a significant interest in constructing controllable, stem cell-based models of human embryo and organs (embryoids / organoids).  The controllability and reproducibility of these human development models, coupled with the ea
10 Juil
2024
Séminaire
11h-23h
Centre de recherche - Paris - Amphithéâtre Marie Curie
Engineering fluorescent biosensors to spy on cell signaling and metabolism
The ever-broadening selection of high performance fluorescent protein (FP)-based biosensors is revolutionizing our ability to spy on the otherwise invisible world of intracellular signalling and metabolism. In this seminar I will describe our most recent efforts to use protein engineering to make a new generation of genetically encoded biosensors, and chemigenetic biosensors augmented with synthet
3 Juil
2024
Séminaire
11h-23h
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
Molecular assembly and mechanics of single vimentin intermediate filaments
Intermediate filaments (IF) are involved in key cellular functions including polarization, migration, and protection against large deformations. These functions are related to their remarkable ability to extend without breaking, a capacity that should be determined by the molecular organization of subunits within filaments. However, this structure-mechanics relationship remains poorly understood a
26 juin
2024
Séminaire
11h-23h
Centre de recherche - Paris - Amphithéâtre Marie Curie
Bees, flowers and electrostatics: a window on a new sensory ecology
Working together to exchange nutrition for pollination services, bees and flowers interact relying on vision, olfaction, touch, and humidity sensing. We have discovered that bees can also detect and learn about the weak electric field that arises as they approach a flower. This electric field – a small force-  is gene
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