Brevet : EP3521283

Pierre Roux, Florence Mahuteau-Betzer, Romain Najman, Jamal Tazi, Gilles Gadea (07.08.2019)

Composés utiles pour le traitement du cancer

European patent application : EP3521283

Résumé

The present invention relates to compound (I)wherein:R independently represents a hydrogen atom, a halogen atom or a group chosen among a -CN group, a hydroxyl group, a -COORgroup, a (C-C)fluoroalkyl group, a (C-C)fluoroalkoxy group, a -NOgroup, a -NRRgroup, a (C-C)alkoxy group, a phenoxy group and a (C-C)alkyl group; Rand Rare independently a hydrogen atom or a (C-C)alkyl group; n is 1, 2 or 3; n’ is 1 or 2; R’ is a hydrogen atom, a halogen atom or a group chosen among a (C-C)alkyl group, a hydroxyl group, a -COORgroup, a -NOgroup, a -NRRgroup, a morpholinyl or a morpholino group, a N-methylpiperazinyl group, a (C-C)fluoroalkyl group, a (C-C)alkoxy group and a -CN group; R » is a hydrogen atom or a (C-C)alkyl group, and Z is C, V is C, Y is C, X is C, T is N, U is C and W is C, for use as an agent for preventing, inhibiting or treating cancer.Some of said compounds are new and also form part of the invention.