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Unité
PIERRE LEOPOLD
Génétique et biologie du développement (UMR3215 / U934)

L’unité de recherche « Génétique et Biologie du Développement » de l’Institut Curie se compose de neuf équipes abordant des questions fondamentales relatives au développement des organismes et à ses dérèglements pathologiques.

Chiffres-clés
16
publications en 2020
3
ERC en cours en 2020
24
Doctorants en thèse en 2020
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Événements scientifiques
3 Juil
2024
Séminaire
11h-23h
Centre de recherche - Paris - Amphithéâtre Hélène Martel-Massignac (BDD)
Building a Multimodal Atlas of Vertebrate Development
Elucidating the developmental processes of organisms requires a comprehensive understanding of cell lineages across spatial, temporal, and molecular dimensions. Advances in imaging and omics technologies allow us to generate technically challenging multidimensional datasets that capture developmental dynamics at unprecedented resolution and across scales (from molecule to organism). In this talk,
6 juin
2024
Séminaire institutionnel "Mayent - Rothschild"
10h-23h
Centre de recherche - Paris - Amphithéâtre Hélène Martel-Massignac (BDD)
THE GENERATION OF NEURONAL DIVERSITY AND ITS EVOLUTION
In the Drosophila optic lobes, ~200 types of neurons organized as 800 columns process the inputs from 800 unit-eyes. We study how this variety of neurons is generated during development and how connectivity among these neurons is regulated

            The ~800 Neural stem cells in the medulla sequentially express a series of temporal transc
30 mai
2024
Séminaire Keynote BDD
10h-23h
Centre de recherche - Paris - Amphithéâtre Hélène Martel-Massignac (BDD)
Coping with mechanical stress: tissue dynamics during development, homeostasis and repair.
 


Abstract:

During growth and development, tissue dynamics, such as tissue folding, cell intercalations and oriented cell divisions, are critical for shaping tissues and organs. However, less is known about how tissues regulate their dynamics during tissue homeostasis and repair, to maintain their shape after development. In this talk, we will discuss how mechanical forces can influen
2 mai
2024
Séminaire institutionnel "Mayent - Rothschild"
11h-23h
Centre de recherche - Orsay - Amphithéâtre du Bâtiment 111
THE GENERATION OF NEURONAL DIVERSITY AND ITS EVOLUTION
Claude Desplan1,2, Nikos Konstantinides1, Felix Simon1, Neset Ozel1, Isabel Holguera1, Jennifer Malin1, Yen Chen1, and Bogdan Sieriebriennikov1

 

1 Center for Developmental Genetics, Department of Biology, New York University, New York, USA; 2 Center for Genomics and System Biology, NYU Abu Dhabi, UAE.

 

            In th
2 mai
2024
Séminaire Keynote BDD
10h-23h
Centre de recherche - Paris - Amphithéâtre Hélène Martel-Massignac (BDD)
Common threads in regeneration: mechano-chemical insights from a jellyfish model
How randomly injured animals can appropriately re-establish positional information and control the deployment of repair programs are key questions of regenerative biology. The hydrozoan jellyfish Clytia hemisphaerica has recently emerged as an original model organism for probing repair phenomena, thanks to its remarkable regenerative abilities. Coping with frequent injuries in the planktonic envir
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