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Génétique et biologie du développement (UMR3215 / U934)

L’unité de recherche « Génétique et Biologie du Développement » de l’Institut Curie se compose de neuf équipes abordant des questions fondamentales relatives au développement des organismes et à ses dérèglements pathologiques.

publications en 2020
ERC en cours en 2020
Doctorants en thèse en 2020
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28 Mar
Centre de recherche - Paris - Amphithéâtre Hélène Martel-Massignac (BDD)
Spatiotemporal models of mammalian development: An epigeneticist’s dream or nightmare?
My research group aims to address the fundamental challenge of understanding how multicellular organisms achieve variation despite cells having identical genetic information. The development of a single fertilized egg into a complete mammalian embryo is an especially beautiful embodiment of this problem. During this process, cellular differentiation is defined by the capacity of the cell ensemble
29 fév
Centre de recherche - Paris - Amphithéâtre Marie Curie
Metabolism of neural stem cell-niche interactions
Metabolism of neural stem cell – niche interactions

While almost all eukaryotic cells require mitochondrial energy production, not all cells and tissues are equally susceptible to mitochondrial disease. In our lab, we mainly study how mitochondrial dysfunction and mutations in the mitochondrial genome affect neural stem cell (NSC) behaviour in Drosophila and mouse. Our
21 Sep
Séminaire Keynote BDD
Centre de recherche - Paris - Amphithéâtre Marie Curie
A Circuit Approach to Understand Aging
Uri Alon´s laboratory is focused on several aspects of systems biology, which intersect well with fundamental biological questions addressed by different groups in our unit, and span from investigating gene expression regulation, tissue homeostasis and morphogenesis, network motifs and the design principles of biological circuits. By combining computational biology, mathematical modeling and
6 Juil
Séminaire Keynote BDD
Centre de recherche - Paris - Amphithéâtre Hélène Martel-Massignac (BDD)
Cellular and environmental mechanisms regulating protein absorption in the vertebrate gut
Intestinal epithelial cells (IECs) are highly polarized and can perform vectorial transport of nutrients using asymmetrically localized membrane proteins and via polarized endocytic and trafficking processes. Using cell biological, forward and reverse genetics, and physiology approaches, we have been investigating mechanisms regulating cell polarization and protein absorption in zebrafish and mice
3 Juil
Séminaire institutionnel "Mayent - Rothschild"
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
Eat Like the Animals: what nature teaches us about the science of healthy eating
Animals from cockroaches to baboons in the wild instinctively mix a healthy, balanced diet. Why can’t we? In this lecture I describe my 35-year research journey with colleague David Raubenheimer to discover the answers to this question. Our scientific detective story involves (among other things) a mediaeval woodland in Oxford, biblical African swarms, cannibal Mormons crickets, a new explan
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